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1

Curcumin and Emodin Down-Regulate TGF-β Signaling Pathway in Human Cervical Cancer Cells

Thacker, Pooja Chandrakant, Karunagaran, Devarajan, Asselin, Eric

Journal:

Year:

2015

Language:

english

File:

PDF, 12.46 MB

english, 2015

2

Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9

Gopal Srinivas, Ruby John Anto, Priya Srinivas, Subramanian Vidhyalakshmi, Vijayamma Priya Senan, Devarajan Karunagaran

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 566 KB

english, 2003

3

4-Amino-2-arylamino-5-indoloyl/cinnamoythiazoles, analogs of topsentin-class of marine alkaloids, induce apoptosis in HeLa cells

Juneja, Manisha, Vanam, Uma, Paranthaman, Sripriya, Bharathan, Asha, Keerthi, Venugopal S., Reena, Justus K., Rajaram, Rama, Rajasekharan, Kallikat N., Karunagaran, Devarajan

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.71 MB

english, 2013

4

Plumbagin Downregulates Wnt Signaling Independent of p53 in Human Colorectal Cancer Cells

Raghu, Dinesh, Karunagaran, Devarajan

Journal:

Journal of Natural Products

Year:

2014

Language:

english

File:

PDF, 2.41 MB

english, 2014

5

Emodin suppresses Wnt signaling in human colorectal cancer cells SW480 and SW620

Pooja, Thacker, Karunagaran, Devarajan

Journal:

European Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 2.13 MB

english, 2014

6

An integrated approach for mining precise RNA-based cervical cancer staging biomarkers

Banerjee, Satarupa, Karunagaran, Devarajan

Journal:

Year:

2019

Language:

english

File:

PDF, 7.36 MB

english, 2019

7

Identification of mRNA and non-coding RNA hubs using network analysis in organ tropism regulated triple negative breast cancer metastasis

Banerjee, Satarupa, Kalyani Yabalooru, Surya Radhika, Karunagaran, Devarajan

Journal:

Computers in Biology and Medicine

Year:

2020

File:

PDF, 5.35 MB

2020

8

Biological and chemical inhibitors of NF-κB sensitize SiHa cells to cisplatin-induced apoptosis

Manickam Venkatraman, Ruby John Anto, Asha Nair, Merina Varghese, Devarajan Karunagaran

Journal:

Molecular Carcinogenesis

Year:

2005

Language:

english

File:

PDF, 325 KB

english, 2005

9

Biophysical evaluation of two red-shifted hypocrellin B derivatives as novel PDT agents

Bibbin T. Paul, Mani S. Babu, Thankayyan R. Santhoshkumar, Devarajan Karunagaran, Govindan S. Selvam, Kevin Brown, Thomas Woo, Sanjay Sharma, Selvaraj Naicker, Ramachandran Murugesan

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2009

Language:

english

File:

PDF, 585 KB

english, 2009

10

Changes in expression, and/or mutations in TGF-β receptors (TGF-β RI and TGF-β RII) and Smad 4 in human ovarian tumors

Marie Lue Antony, Rema Nair, Paul Sebastian, Devarajan Karunagaran

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2010

Language:

english

File:

PDF, 613 KB

english, 2010

11

Mapping of adenovirus 5 E1A domains responsible for suppression of neu-mediated transformation via transcriptional repression of neu

Chen, Hua, Yu, Dihua, Chinnadurai, G, Karunagaran, Devarajan, Hung, Mien-Chie

Journal:

Year:

1997

Language:

english

File:

PDF, 448 KB

english, 1997

12

Involvement of cdc2-mediated phosphorylation in the cell cycle-dependent regulation of p185neu

Kiyokawa, Nobutaka, Karunagaran, Devarajan, Lee, Eun Kyung, Xie, Youming, Yan, Duen-Hwa, Hung, Mien-Chie

Journal:

Year:

1997

Language:

english

File:

PDF, 464 KB

english, 1997

13

NF-κB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix

Nair, Asha, Venkatraman, Manickam, Maliekal, Tessy T, Nair, Balaraman, Karunagaran, Devarajan

Journal:

Year:

2003

Language:

english

File:

PDF, 582 KB

english, 2003

14

Loss of expression, and mutations of Smad 2 and Smad 4 in human cervical cancer

Maliekal, Tessy T, Antony, Marie-Lue, Nair, Asha, Paulmurugan, Ramasamy, Karunagaran, Devarajan

Journal:

Year:

2003

Language:

english

File:

PDF, 343 KB

english, 2003

15

Chlorophyll Revisited: Anti-inflammatory Activities of Chlorophyll a and Inhibition of Expression of TNF-α Gene by the Same

Appian Subramoniam, Velikkakathu V. Asha, Sadasivan Ajikumaran Nair, Sreejith P. Sasidharan, Parameswaran K. Sureshkumar, Krishnan Nair Rajendran, Devarajan Karunagaran, Krishnan Ramalingam

Journal:

Year:

2012

Language:

english

File:

PDF, 308 KB

english, 2012

16

Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells

Shlomit Erlich, Pazit Tal-Or, Ronit Liebling, Roy Blum, Devarajan Karunagaran, Yoel Kloog, Ronit Pinkas-Kramarski

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 642 KB

english, 2006

17

Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells

Suby Oommen, Ruby John Anto, Gopal Srinivas, Devarajan Karunagaran

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 311 KB

english, 2004

18

Nimbolide, a neem limonoid abrogates canonical NF-κB and Wnt signaling to induce caspase-dependent apoptosis in human hepatocarcinoma (HepG2) cells

Krishnamurthy Kavitha, Ramamurthi Vidya Priyadarsini, Prabukumar Anitha, Krishnan Ramalingam, Ramasamy Sakthivel, Gempuraj Purushothaman, Abhishek Kumar Singh, Devarajan Karunagaran, Siddavaram Nagini

Journal:

European Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.59 MB

english, 2012

19

Of humans and canines: A comparative evaluation of heat shock and apoptosis-associated proteins in mammary tumors

Ramasamy Kumaraguruparan, Devarajan Karunagaran, Chidambaram Balachandran, Baktavachalam Murali Manohar, Siddavaram Nagini

Journal:

Clinica Chimica Acta

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

20

Quercetin attenuates Monocyte Chemoattractant Protein-1 gene expression in glucose primed aortic endothelial cells through NF-κB and AP-1

Sumith Retnamma Panicker, Prethish Sreenivas, Mani Sankar Babu, Devarajan Karunagaran, Chandrasekharan Cheranellore Kartha

Journal:

Pharmacological Research

Year:

2010

Language:

english

File:

PDF, 899 KB

english, 2010

21

N-Substituted 1,2-Dihydroquinolines as Anticancer Agents: Electronic Control of Redox Stability, Assessment of Antiproliferative Effects, and Mechanistic Insights

John Victor, Napoleon, Sakthivel, Ramasamy, Muraleedharan, Kannoth Manheri, Karunagaran, Devarajan

Journal:

Year:

2013

Language:

english

File:

PDF, 1.51 MB

english, 2013

22

MicroRNA-106b-25 cluster targets β-TRCP2, increases the expression of Snail and enhances cell migration and invasion in H1299 (non small cell lung cancer) cells

Savita, Udainiya, Karunagaran, Devarajan

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 1.71 MB

english, 2013

23

HPV16 E2-mediated potentiation of NF-κB activation induced by TNF-α involves parallel activation of STAT3 with a reduction in E2-induced apoptosis

Prabhavathy, Devan, Prabhakar, Bandaru Niranjana, Karunagaran, Devarajan

Journal:

Molecular and Cellular Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

24

Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives

Sreelatha, Thonthula, Kandhasamy, Subramani, Dinesh, Raghu, Shruthy, Suresh, Shweta, Sinha, Mukesh, Doble, Karunagaran, Devarajan, Balaji, Ravichandran, Mathivanan, Narayanasamy, Perumal, Paramasivan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 852 KB

english, 2014

25

MiR-29b downregulates canonical Wnt signaling by targeting BCL9L and other coactivators of β-catenin in human colorectal cancer cells

Subramanian, Maitreyi, Rao, Srinivasa R., Thacker, Pooja, Chatterjee, Suvro, Karunagaran, Devarajan

Journal:

Journal of Cellular Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

26

HPV16 E2 enhances the expression of NF-κB and STAT3 target genes and potentiates NF-κB activation by inflammatory mediators

Prabhavathy, Devan, Vijayalakshmi, Ramprasath, Kanchana, M. Padhmanaban, Karunagaran, Devarajan

Journal:

Cellular Immunology

Year:

2014

Language:

english

File:

PDF, 1.77 MB

english, 2014

27

Benzisothiazolones arrest the cell cycle at the G2/M phase and induce apoptosis in HeLa cells

Gopinath, Pushparathinam, Ramalingam, Krishnan, Muraleedharan, Kannoth Manheri, Karunagaran, Devarajan

Journal:

Year:

2013

Language:

english

File:

PDF, 348 KB

english, 2013

28

Re-expression of HPV16 E2 in SiHa (human cervical cancer) cells potentiates NF-κB activation induced by TNF-α concurrently increasing senescence and survival

Prabhavathy, Devan, Subramanian, Chandrasekaran Karthik, Karunagaran, Devarajan

Journal:

Bioscience Reports

Year:

2015

Language:

english

File:

PDF, 1.30 MB

english, 2015

29

ChemInform Abstract: N-Substituted 1,2-Dihydroquinolines as Anticancer Agents: Electronic Control of Redox Stability, Assessment of Antiproliferative Effects, and Mechanistic Insights.

Victor, Napoleon John, Sakthivel, Ramasamy, Muraleedharan, Kannoth Manheri, Karunagaran, Devarajan

Journal:

Year:

2014

File:

PDF, 24 KB

2014

30

Three dimensional structure of the closed conformation (active) of human merlin reveals masking of actin binding site in the FERM domain

Sivakumar, Krishnankutty C., Thomas, Biju, Karunagaran, Devarajan

Journal:

International Journal of Bioinformatics Research and Applications

Year:

2009

Language:

english

File:

PDF, 3.90 MB

english, 2009

31

Downregulation ofHMGB1bymiR-34ais sufficient to suppress proliferation, migration and invasion of human cervical and colorectal cancer cells

Chandrasekaran, Karthik Subramanian, Sathyanarayanan, Anusha, Karunagaran, Devarajan

Journal:

Year:

2016

Language:

english

File:

PDF, 1.92 MB

english, 2016

32

MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells

Chandrasekaran, Karthik Subramanian, Sathyanarayanan, Anusha, Karunagaran, Devarajan

Journal:

British Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 1.56 MB

english, 2016

33

microRNA-146a inhibits proliferation, migration and invasion of human cervical and colorectal cancer cells

Sathyanarayanan, Anusha, Chandrasekaran, Karthik Subramanian, Karunagaran, Devarajan

Journal:

Biochemical and Biophysical Research Communications

Year:

2016

Language:

english

File:

PDF, 881 KB

english, 2016

34

microRNA-145modulates epithelial-mesenchymal transition and suppresses proliferation, migration and invasion by targetingSIP1in human cervical cancer cells

Sathyanarayanan, Anusha, Chandrasekaran, Karthik Subramanian, Karunagaran, Devarajan

Journal:

Cellular Oncology

Year:

2017

Language:

english

File:

PDF, 1.82 MB

english, 2017

35

Reply: Comment on ‘MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells’

Chandrasekaran, Karthik Subramanian, Sathyanarayanan, Anusha, Karunagaran, Devarajan

Journal:

British Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 66 KB

english, 2017

36

microRNA-145 downregulates SIP1 -expression but differentially regulates proliferation, migration, invasion and Wnt signalling in SW480 and SW620 cells

Sathyanarayanan, Anusha, Chandrasekaran, Karthik Subramanian, Karunagaran, Devarajan

Journal:

Journal of Cellular Biochemistry

Year:

2017

Language:

english

File:

PDF, 873 KB

english, 2017

37

miR-214 activates TP53 but suppresses the expression of RELA, CTNNB1, and STAT3 in human cervical and colorectal cancer cells

Chandrasekaran, Karthik Subramanian, Sathyanarayanan, Anusha, Karunagaran, Devarajan

Journal:

Cell Biochemistry and Function

Year:

2017

Language:

english

File:

PDF, 400 KB

english, 2017

38

Menadione Induced Reset of Circadian Superoxide Rhythms in Human Colon Cancer Cells

Uma, K, Palukuri, Meghana Venkata, Karunagaran, Devarajan, Rengasamy, Raghunathan, Suraishkumar, G K

Journal:

Free Radical Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 98 KB

english, 2017

39

Advances in Chalcones with Anticancer Activities

Karthikeyan, Chandrabose, Narayana Moorthy, Narayana S.H., Ramasamy, Sakthivel, Vanam, Uma, Manivannan, Elangovan, Karunagaran, Devarajan, Trivedi, Piyush

Journal:

Recent Patents on Anti-Cancer Drug Discovery

Year:

2014

Language:

english

File:

PDF, 980 KB

english, 2014

40

Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-κ B and the serine/threonine kinase Akt and is independent of tubulin polymerization.

Bava, Smitha V., Puliyappadamba, Vineshkumar T., Deepti, Ayswaria, Nair, Asha, Karunagaran, Devarajan, Anto, Ruby John

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 50 KB

english, 2018

41

Entrainment of superoxide rhythm by menadione in HCT116 colon cancer cells

Kizhuveetil, Uma, Palukuri, Meghana V., Sharma, Priyanshu, Karunagaran, Devarajan, Rengaswamy, Raghunathan, Suraishkumar, G. K.

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.82 MB

english, 2019

42

A novel reporter system for cyclic AMP mediated gene expression in mammalian cells based on synthetic transgene expression system

Durai, Latha, Vijayalakshmi, Ramshankar, Karunagaran, Devarajan

Journal:

European Journal of Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.02 MB

english, 2019

43

A novel reporter system for cyclic AMP mediated gene expression in mammalian cells based on synthetic transgene expression system

Durai, Latha, Vijayalakshmi, Ramshankar, Karunagaran, Devarajan

Journal:

European Journal of Pharmacology

Year:

2019

File:

PDF, 1.02 MB

2019

44

An integrated approach for mining precise RNA-based cervical cancer staging biomarkers

Banerjee, Satarupa, Karunagaran, Devarajan

Journal:

Year:

2019

File:

PDF, 7.36 MB

2019

45

Reactive Pt(II) center as part of redox-active quinoline-based heterocyclic scaffolds toward new anticancer leads

Kumbhakonam, Sateeshkumar, Saroj, Soumya, Venkatesan, Nalini, Devarajan, Karunagaran, Manheri, Muraleedharan K.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 2.36 MB

2020

46

Regulation of Hippo signaling pathway in cancer: A MicroRNA perspective

Samji, Priyanka, Rajendran, Manoj K., Warrier, Vidya P., Ganesh, Akshayaa, Devarajan, Karunagaran

Journal:

Cellular Signalling

Year:

2020

File:

PDF, 2.01 MB

2020